Understanding Alport Syndrome: A Complete Guide
Alport Syndrome severely impacts your kidney, eyes and ears. Read on further to understand how Alport Syndrome is diagnosed and managed at Phoenix Medical Centre with a nephrology doctor’s personalized care and treatment options. What is Alport Syndrome? Alport Syndrome is a genetic disorder that impacts kidney function. This leads to Glomerulonephriti ( inflammation of the kidney's filtering units). It also affects hearing and vision. The disease is caused by gene mutations that producees collagen, a protein responsible for providing structural support in various tissues. Causes Alport Syndrome is inherited in three main ways: X-Linked : The most common type of syndrome, caused by mutations in the COL4A5 gene on the X chromosome. It affects primarily males, though females can also be carriers. Autosomal Recessive : Caused by mutations in the COL4A3 or COL4A4 genes on non-sex chromosomes. This type affects both males and females equally. Autosomal Dominant ...